Human SEMA5B activation kit by CRISPRa

CAT#: GA110099

SEMA5B CRISPRa kit - CRISPR gene activation of human semaphorin 5B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SEMA5B
• Locus ID: 54437
• Kit Components:

  GA110099G1, SEMA5B gRNA vector 1 in pCas-Guide-CRISPRa

  GA110099G2, SEMA5B gRNA vector 2 in pCas-Guide-CRISPRa

  GA110099G3, SEMA5B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001031702, NM_001256346, NM_001256347, NM_001256348, NM_018987, NR_046079
• Synonyms: SEMAG; SemG
• Summary: This gene encodes a member of the semaphorin protein family which regulates axon growth during development of the nervous system. The encoded protein has a characteristic Sema domain near the N-terminus, through which semaphorins bind to plexin, and five thrombospondin type 1 repeats in the C-terminal region of the protein. The protein product may be cleaved and exist as a secreted molecule (PMID: 19463192). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]