Human DHX29 activation kit by CRISPRa

CAT#: GA110144

DHX29 CRISPRa kit - CRISPR gene activation of human DExH-box helicase 29

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DHX29
• Locus ID: 54505
• Kit Components:

  GA110144G1, DHX29 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110144G2, DHX29 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110144G3, DHX29 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001345964, NM_001345965, NM_019030, NR_144323, NR_144324, NR_144325
• Synonyms: DDX29
• Summary: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein functions in translation initiation, and is specifically required for ribosomal scanning across stable mRNA secondary structures during initiation codon selection. This protein may also play a role in sensing virally derived cytosolic nucleic acids. Knockdown of this gene results in reduced protein translation and impaired proliferation of cancer cells. [provided by RefSeq, Sep 2016]