Human PAF1 activation kit by CRISPRa

CAT#: GA110203

PAF1 CRISPRa kit - CRISPR gene activation of human PAF1 homolog, Paf1/RNA polymerase II complex component

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PAF1
• Locus ID: 54623
• Kit Components:

  GA110203G1, PAF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110203G2, PAF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110203G3, PAF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256826, NM_019088, NR_046384
• Synonyms: F23149_1; PD2
• Summary: This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]