Human CROT activation kit by CRISPRa

CAT#: GA110218

CROT CRISPRa kit - CRISPR gene activation of human carnitine O-octanoyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CROT
• Locus ID: 54677
• Kit Components:

  GA110218G1, CROT gRNA vector 1 in pCas-Guide-CRISPRa

  GA110218G2, CROT gRNA vector 2 in pCas-Guide-CRISPRa

  GA110218G3, CROT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001143935, NM_001243745, NM_021151, NR_026585
• Synonyms: COT
• Summary: This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]