Human LEPROT activation kit by CRISPRa

CAT#: GA110237

LEPROT CRISPRa kit - CRISPR gene activation of human leptin receptor overlapping transcript


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol LEPROT
Locus ID 54741
Kit Components

GA110237G1, LEPROT gRNA vector 1 in pCas-Guide-CRISPRa

GA110237G2, LEPROT gRNA vector 2 in pCas-Guide-CRISPRa

GA110237G3, LEPROT gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001198681, NM_001198683, NM_017526
Synonyms LEPR; OB-RGRP; OBRGRP; VPS55
Summary LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]). [supplied by OMIM, Jul 2010]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.