Human LEPROT activation kit by CRISPRa
CAT#: GA110237
LEPROT CRISPRa kit - CRISPR gene activation of human leptin receptor overlapping transcript
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | LEPROT |
Locus ID | 54741 |
Kit Components | GA110237G1, LEPROT gRNA vector 1 in pCas-Guide-CRISPRa GA110237G2, LEPROT gRNA vector 2 in pCas-Guide-CRISPRa GA110237G3, LEPROT gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001198681, NM_001198683, NM_017526 |
Synonyms | LEPR; OB-RGRP; OBRGRP; VPS55 |
Summary | LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]). [supplied by OMIM, Jul 2010] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN408878 | LEPROT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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