Human DPP8 activation kit by CRISPRa

CAT#: GA110335

DPP8 CRISPRa kit - CRISPR gene activation of human dipeptidyl peptidase 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DPP8
• Locus ID: 54878
• Kit Components:

  GA110335G1, DPP8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110335G2, DPP8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110335G3, DPP8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017743, NM_130434, NM_197960, NM_197961, NM_001320875, NM_001320876, NR_135485, NR_135486
• Synonyms: DP8; DPRP1; MSTP141
• Summary: This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]