Human plasticity related gene 3 (PLPPR1) activation kit by CRISPRa

CAT#: GA110343

PLPPR1 CRISPRa kit - CRISPR gene activation of human phospholipid phosphatase related 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLPPR1
• Locus ID: 54886
• Kit Components:

  GA110343G1, PLPPR1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110343G2, PLPPR1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110343G3, PLPPR1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017753, NM_207299
• Synonyms: LPPR1; PRG-3
• Summary: This gene encodes a member of the plasticity-related gene (PRG) family. Members of the PRG family mediate lipid phosphate phosphatase activity in neurons and are known to be involved in neuronal plasticity. The protein encoded by this gene does not perform its function through enzymatic phospholipid degradation. This gene is strongly expressed in brain. It shows dynamic expression regulation during brain development and neuronal excitation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]