Human CEP55 activation kit by CRISPRa

CAT#: GA110567

CEP55 CRISPRa kit - CRISPR gene activation of human centrosomal protein 55

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CEP55
• Locus ID: 55165
• Kit Components:

  GA110567G1, CEP55 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110567G2, CEP55 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110567G3, CEP55 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001127182, NM_018131
• Synonyms: C10orf3; CT111; URCC6
• Summary: Plays a role in mitotic exit and cytokinesis (PubMed:16198290, PubMed:17853893). Recruits PDCD6IP and TSG101 to midbody during cytokinesis. Required for successful completion of cytokinesis (PubMed:17853893). Not required for microtubule nucleation (PubMed:16198290). Plays a role in the development of the brain and kidney (PubMed:28264986). [UniProtKB/Swiss-Prot Function]