Human UBE2W activation kit by CRISPRa

CAT#: GA110672

UBE2W CRISPRa kit - CRISPR gene activation of human ubiquitin conjugating enzyme E2 W

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UBE2W
• Locus ID: 55284
• Kit Components:

  GA110672G1, UBE2W gRNA vector 1 in pCas-Guide-CRISPRa

  GA110672G2, UBE2W gRNA vector 2 in pCas-Guide-CRISPRa

  GA110672G3, UBE2W gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001481, NM_001001482, NM_001271015, NM_018299, NR_073119, NR_073120, NR_073121
• Synonyms: UBC-16; UBC16
• Summary: This gene encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]