Human YOD1 activation kit by CRISPRa

CAT#: GA110751

YOD1 CRISPRa kit - CRISPR gene activation of human YOD1 deubiquitinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: YOD1
• Locus ID: 55432
• Kit Components:

  GA110751G1, YOD1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110751G2, YOD1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110751G3, YOD1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001276320, NM_018566
• Synonyms: DUBA8; OTUD2; PRO0907
• Summary: Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. The protein encoded by this gene belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]