Human HES6 activation kit by CRISPRa

CAT#: GA110761

HES6 CRISPRa kit - CRISPR gene activation of human hes family bHLH transcription factor 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HES6
• Locus ID: 55502
• Kit Components:

  GA110761G1, HES6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110761G2, HES6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110761G3, HES6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142853, NM_001282434, NM_018645
• Synonyms: bHLHb41; bHLHc23; C-HAIRY1; HES-6
• Summary: This gene encodes a member of a subfamily of basic helix-loop-helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of this gene family regulate cell differentiation in numerous cell types. The protein encoded by this gene functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C-terminus. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2008]