Human KIF21A activation kit by CRISPRa

CAT#: GA110816

KIF21A CRISPRa kit - CRISPR gene activation of human kinesin family member 21A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KIF21A
• Locus ID: 55605
• Kit Components:

  GA110816G1, KIF21A gRNA vector 1 in pCas-Guide-CRISPRa

  GA110816G2, KIF21A gRNA vector 2 in pCas-Guide-CRISPRa

  GA110816G3, KIF21A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001173463, NM_001173464, NM_001173465, NM_017641
• Synonyms: CFEOM1; FEOM1; FEOM3A
• Summary: This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]