Human DOCK10 activation kit by CRISPRa

CAT#: GA110828

DOCK10 CRISPRa kit - CRISPR gene activation of human dedicator of cytokinesis 10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DOCK10
• Locus ID: 55619
• Kit Components:

  GA110828G1, DOCK10 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110828G2, DOCK10 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110828G3, DOCK10 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001290263, NM_014689, NM_017718, NM_001363762
• Synonyms: DRIP2; Nbla10300; ZIZ3
• Summary: This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins, which also contain an N-terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Mar 2014]