Human SMPD4 activation kit by CRISPRa

CAT#: GA110836

SMPD4 CRISPRa kit - CRISPR gene activation of human sphingomyelin phosphodiesterase 4

SDS

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol SMPD4
Locus ID 55627
Kit Components

GA110836G1, SMPD4 gRNA vector 1 in pCas-Guide-CRISPRa

GA110836G2, SMPD4 gRNA vector 2 in pCas-Guide-CRISPRa

GA110836G3, SMPD4 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058
Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001171083, NM_001171084, NM_017751, NM_017951, NR_033230, NR_033231, NR_033232
Synonyms NET13; NSMASE-3; NSMASE3
Summary The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network. [provided by RefSeq, Mar 2017]

Other Versions

SKU Description Size Price
KN414161 SMPD4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.