Human OSGEP activation kit by CRISPRa

CAT#: GA110849

OSGEP CRISPRa kit - CRISPR gene activation of human O-sialoglycoprotein endopeptidase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: OSGEP
• Locus ID: 55644
• Kit Components:

  GA110849G1, OSGEP gRNA vector 1 in pCas-Guide-CRISPRa

  GA110849G2, OSGEP gRNA vector 2 in pCas-Guide-CRISPRa

  GA110849G3, OSGEP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017807
• Synonyms: GCPL1; KAE1; OSGEP1; PRSMG1
• Summary: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. [UniProtKB/Swiss-Prot Function]