Human NSUN5 activation kit by CRISPRa

CAT#: GA110889

NSUN5 CRISPRa kit - CRISPR gene activation of human NOP2/Sun RNA methyltransferase 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NSUN5
• Locus ID: 55695
• Kit Components:

  GA110889G1, NSUN5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110889G2, NSUN5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110889G3, NSUN5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001168347, NM_001168348, NM_018044, NM_148956
• Synonyms: NOL1; NOL1R; NSUN5A; p120; p120(NOL1); WBSCR20; WBSCR20A
• Summary: This gene encodes a member of an evolutionarily conserved family of proteins that may function as methyltransferases. This gene is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. There are two pseudogenes for this gene located in the same region of chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]