Human OGDHL activation kit by CRISPRa

CAT#: GA110939

OGDHL CRISPRa kit - CRISPR gene activation of human oxoglutarate dehydrogenase like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: OGDHL
• Locus ID: 55753
• Kit Components:

  GA110939G1, OGDHL gRNA vector 1 in pCas-Guide-CRISPRa

  GA110939G2, OGDHL gRNA vector 2 in pCas-Guide-CRISPRa

  GA110939G3, OGDHL gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001143996, NM_001143997, NM_018245, NM_001347819, NM_001347820, NM_001347821, NM_001347822, NM_001347823, NM_001347824, NM_001347825, NM_001347826, NR_144682, NR_144683, NR_144684, NR_144685, NR_144686
• Summary: The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. The encoded protein down-regulates the AKT signaling cascade and can suppress the growth of cervical cancer cells. [provided by RefSeq, Dec 2016]