Human CDK5RAP2 activation kit by CRISPRa

CAT#: GA110941

CDK5RAP2 CRISPRa kit - CRISPR gene activation of human CDK5 regulatory subunit associated protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDK5RAP2
• Locus ID: 55755
• Kit Components:

  GA110941G1, CDK5RAP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110941G2, CDK5RAP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110941G3, CDK5RAP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001011649, NM_001272039, NM_018249, NR_073554, NR_073555, NR_073556, NR_073557, NR_073558
• Synonyms: C48; Cep215; MCPH3
• Summary: This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]