Human C6orf70 (ERMARD) activation kit by CRISPRa

CAT#: GA110963

ERMARD CRISPRa kit - CRISPR gene activation of human ER membrane associated RNA degradation

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ERMARD
• Locus ID: 55780
• Kit Components:

  GA110963G1, ERMARD gRNA vector 1 in pCas-Guide-CRISPRa

  GA110963G2, ERMARD gRNA vector 2 in pCas-Guide-CRISPRa

  GA110963G3, ERMARD gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278531, NM_001278532, NM_001278533, NM_018341
• Synonyms: C6orf70; dJ266L20.3; PVNH6
• Summary: The protein encoded by this gene contains 2 transmembrane domains near the C-terminus and is localized in the endoplasmic reticulum. Knockout of this gene in developing rat brain showed that it may be involved in neuronal migration. Mutations in this gene are associated with periventricular nodular heterotopia-6 (PVNH6). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]