Human SCN3B activation kit by CRISPRa

CAT#: GA110980

SCN3B CRISPRa kit - CRISPR gene activation of human sodium voltage-gated channel beta subunit 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SCN3B
• Locus ID: 55800
• Kit Components:

  GA110980G1, SCN3B gRNA vector 1 in pCas-Guide-CRISPRa

  GA110980G2, SCN3B gRNA vector 2 in pCas-Guide-CRISPRa

  GA110980G3, SCN3B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001040151, NM_018400
• Synonyms: ATFB16; BRGDA7; HSA243396; SCNB3
• Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]