Human DCP1A activation kit by CRISPRa

CAT#: GA110982

DCP1A CRISPRa kit - CRISPR gene activation of human decapping mRNA 1A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DCP1A
• Locus ID: 55802
• Kit Components:

  GA110982G1, DCP1A gRNA vector 1 in pCas-Guide-CRISPRa

  GA110982G2, DCP1A gRNA vector 2 in pCas-Guide-CRISPRa

  GA110982G3, DCP1A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001290204, NM_001290205, NM_001290206, NM_001290207, NM_018403
• Synonyms: HSA275986; Nbla00360; SMAD4IP1; SMIF
• Summary: Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]