Human TMEM126B activation kit by CRISPRa

CAT#: GA111029

TMEM126B CRISPRa kit - CRISPR gene activation of human transmembrane protein 126B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TMEM126B
• Locus ID: 55863
• Kit Components:

  GA111029G1, TMEM126B gRNA vector 1 in pCas-Guide-CRISPRa

  GA111029G2, TMEM126B gRNA vector 2 in pCas-Guide-CRISPRa

  GA111029G3, TMEM126B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001193537, NM_001193538, NM_001256546, NM_001256547, NM_018480, NR_036465, NM_001350393, NM_001350394, NM_001350395, NM_001350396, NR_146645, NR_146646
• Synonyms: HT007
• Summary: This gene encodes a mitochondrial transmembrane protein which is a component of the mitochondrial complex I assembly complex. The encoded protein serves as an assembly factor that is required for formation of the membrane arm of the complex. It interacts with NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 13. Naturally occurring mutations in this gene are associated with isolated complex I deficiency. A pseudogene of this gene has been defined on chromosome 9. [provided by RefSeq, Apr 2017]