Human KLHL9 activation kit by CRISPRa

CAT#: GA111070

KLHL9 CRISPRa kit - CRISPR gene activation of human kelch like family member 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KLHL9
• Locus ID: 55958
• Kit Components:

  GA111070G1, KLHL9 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111070G2, KLHL9 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111070G3, KLHL9 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001040713, NM_018847
• Synonyms: RP11-380P16.6
• Summary: This gene encodes a protein that belongs to the kelch repeat-containing family, and contains an N-terminal BTB/POZ domain, a BACK domain and six C-terminal kelch repeats. The encoded protein is a component of a complex with cullin 3-based E3 ligase, which plays a role in mitosis. This protein complex is a cell cycle regulator, and functions in the organization and integrity of the spindle midzone in anaphase and the completion of cytokinesis. The complex is required for the removal of the chromosomal passenger protein aurora B from mitotic chromosomes. [provided by RefSeq, Jul 2016]