Human PCDHB6 activation kit by CRISPRa

CAT#: GA111122

PCDHB6 CRISPRa kit - CRISPR gene activation of human protocadherin beta 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PCDHB6
• Locus ID: 56130
• Kit Components:

  GA111122G1, PCDHB6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111122G2, PCDHB6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111122G3, PCDHB6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303145, NM_018939
• Synonyms: PCDH-BETA6
• Summary: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. Unlike the alpha and gamma clusters, the transcripts from these genes do not share common 3' exons. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell neural connections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]