Human MRAP activation kit by CRISPRa

CAT#: GA111162

MRAP CRISPRa kit - CRISPR gene activation of human melanocortin 2 receptor accessory protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MRAP
• Locus ID: 56246
• Kit Components:

  GA111162G1, MRAP gRNA vector 1 in pCas-Guide-CRISPRa

  GA111162G2, MRAP gRNA vector 2 in pCas-Guide-CRISPRa

  GA111162G3, MRAP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001285394, NM_178817, NM_206898
• Synonyms: B27; C21orf61; FALP; FGD2; GCCD2
• Summary: This gene encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2. Alternatively spliced transcript variants have been described. [provided by RefSeq, Dec 2009]