Human EIF5A2 activation kit by CRISPRa

CAT#: GA111203

EIF5A2 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 5A2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EIF5A2
• Locus ID: 56648
• Kit Components:

  GA111203G1, EIF5A2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111203G2, EIF5A2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111203G3, EIF5A2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020390
• Synonyms: EIF-5A2; eIF5AII
• Summary: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. [UniProtKB/Swiss-Prot Function]