Human OLFML3 activation kit by CRISPRa

CAT#: GA111290

OLFML3 CRISPRa kit - CRISPR gene activation of human olfactomedin like 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: OLFML3
• Locus ID: 56944
• Kit Components:

  GA111290G1, OLFML3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111290G2, OLFML3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111290G3, OLFML3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001286352, NM_001286353, NM_020190
• Synonyms: HNOEL-iso; OLF44
• Summary: This gene encodes a member of the olfactomedin-like gene family which also includes genes encoding noelin, tiarin, myocilin, amassin, optimedin, photomedin, and latrophilin. The encoded protein is a secreted extracellular matrix glycoprotein with a C-terminal olfactomedin domain that facilitates protein-protein interactions, cell adhesion, and intercellular interactions. It serves as both a scaffold protein that recruits bone morphogenetic protein 1 to its substrate chordin, and as a vascular tissue remodeler with pro-angiogenic properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]