Human PDXP activation kit by CRISPRa

CAT#: GA111341

PDXP CRISPRa kit - CRISPR gene activation of human pyridoxal phosphatase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PDXP
• Locus ID: 57026
• Kit Components:

  GA111341G1, PDXP gRNA vector 1 in pCas-Guide-CRISPRa

  GA111341G2, PDXP gRNA vector 2 in pCas-Guide-CRISPRa

  GA111341G3, PDXP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020315
• Synonyms: CIN; dJ37E16.5; PLP
• Summary: Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 [PubMed 14522954]). [supplied by OMIM, Mar 2008]