Human RARS2 activation kit by CRISPRa

CAT#: GA111345

RARS2 CRISPRa kit - CRISPR gene activation of human arginyl-tRNA synthetase 2, mitochondrial

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RARS2
• Locus ID: 57038
• Kit Components:

  GA111345G1, RARS2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111345G2, RARS2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111345G3, RARS2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001318785, NM_020320, NR_134857, NM_001350505, NM_001350506, NM_001350507, NM_001350508, NM_001350509, NM_001350510, NM_001350511, NR_146738, NR_146739, NR_146740, NR_146741, NR_146742, NR_146743, NR_146744, NR_146745, NR_146746, NR_146747, NR_146748, NR_146749, NR_146750, NR_146751, NR_146752, NR_146753, NR_146754, NR_146755, NR_146756, NR_146757, NR_146758, NR_146759
• Synonyms: ArgRS; DALRD2; dJ382I10.6; PCH6; PRO1992; RARSL
• Summary: This nuclear gene encodes a protein that localizes to the mitochondria, where it catalyzes the transfer of L-arginine to its cognate tRNA, an important step in translation of mitochondrially-encoded proteins. Defects in this gene are a cause of pontocerebellar hypoplasia type 6 (PCH6). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]