Human GJC2 activation kit by CRISPRa

CAT#: GA111420

GJC2 CRISPRa kit - CRISPR gene activation of human gap junction protein gamma 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GJC2
• Locus ID: 57165
• Kit Components:

  GA111420G1, GJC2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111420G2, GJC2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111420G3, GJC2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020435
• Synonyms: CX46.6; Cx47; GJA12; HLD2; LMPH1C; PMLDAR; SPG44
• Summary: This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1. [provided by RefSeq, Jul 2008]