Human TBC1D24 activation kit by CRISPRa

CAT#: GA111510

TBC1D24 CRISPRa kit - CRISPR gene activation of human TBC1 domain family member 24

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TBC1D24
• Locus ID: 57465
• Kit Components:

  GA111510G1, TBC1D24 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111510G2, TBC1D24 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111510G3, TBC1D24 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199107, NM_020705
• Synonyms: DFNA65; DFNB86; DOORS; EIEE16; FIME; TLDC6
• Summary: This gene encodes a protein with a conserved domain, referred to as the TBC domain, characteristic of proteins which interact with GTPases. TBC domain proteins may serve as GTPase-activating proteins for a particular group of GTPases, the Rab (Ras-related proteins in brain) small GTPases which are involved in the regulation of membrane trafficking. Mutations in this gene are associated with familial infantile myoclonic epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]