Human CNOT6 activation kit by CRISPRa

CAT#: GA111517

CNOT6 CRISPRa kit - CRISPR gene activation of human CCR4-NOT transcription complex subunit 6


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol CNOT6
Locus ID 57472
Kit Components

GA111517G1, CNOT6 gRNA vector 1 in pCas-Guide-CRISPRa

GA111517G2, CNOT6 gRNA vector 2 in pCas-Guide-CRISPRa

GA111517G3, CNOT6 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001303241, NM_015455, NM_001370472, NM_001370473, NM_001370474, NR_163437, NR_163438
Synonyms CCR4; Ccr4a
Summary This gene encodes the catalytic component of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates. The CCR4-NOT complex plays a role in many cellular processes, including miRNA-mediated repression, mRNA degradation, and transcriptional regulation. [provided by RefSeq, Dec 2014]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.