Human Alanyl tRNA synthetase 2 (AARS2) activation kit by CRISPRa

CAT#: GA111543

AARS2 CRISPRa kit - CRISPR gene activation of human alanyl-tRNA synthetase 2, mitochondrial

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AARS2
• Locus ID: 57505
• Kit Components:

  GA111543G1, AARS2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111543G2, AARS2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111543G3, AARS2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020745
• Synonyms: AARSL; COXPD8; LKENP; MT-ALARS; MTALARS
• Summary: The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011]