Human PCDH19 activation kit by CRISPRa

CAT#: GA111560

PCDH19 CRISPRa kit - CRISPR gene activation of human protocadherin 19

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PCDH19
• Locus ID: 57526
• Kit Components:

  GA111560G1, PCDH19 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111560G2, PCDH19 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111560G3, PCDH19 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001105243, NM_001184880, NM_020766
• Synonyms: EFMR; EIEE9
• Summary: The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Mutations in this gene on human chromosome X are associated with sporadic infantile epileptic encephalopathy and to a female-restricted form of epilepsy (EFMR; also known as PCDH19RE). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]