Human ARRDC3 activation kit by CRISPRa

CAT#: GA111590

ARRDC3 CRISPRa kit - CRISPR gene activation of human arrestin domain containing 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARRDC3
• Locus ID: 57561
• Kit Components:

  GA111590G1, ARRDC3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111590G2, ARRDC3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111590G3, ARRDC3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001329670, NM_001329671, NM_001329672, NM_020801, NR_138071, NR_138072
• Synonyms: TLIMP
• Summary: This gene encodes a member of the arrestin family of proteins, which regulate G protein-mediated signaling. The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4, a tumor-related antigen, targeting the integrin for internalization and degradation. [provided by RefSeq, Jul 2016]