Human PCDH10 activation kit by CRISPRa

CAT#: GA111602

PCDH10 CRISPRa kit - CRISPR gene activation of human protocadherin 10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PCDH10
• Locus ID: 57575
• Kit Components:

  GA111602G1, PCDH10 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111602G2, PCDH10 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111602G3, PCDH10 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020815, NM_032961
• Synonyms: OL-PCDH; PCDH19
• Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]