Human WDR48 activation kit by CRISPRa

CAT#: GA111623

WDR48 CRISPRa kit - CRISPR gene activation of human WD repeat domain 48


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol WDR48
Locus ID 57599
Kit Components

GA111623G1, WDR48 gRNA vector 1 in pCas-Guide-CRISPRa

GA111623G2, WDR48 gRNA vector 2 in pCas-Guide-CRISPRa

GA111623G3, WDR48 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001303402, NM_001303403, NM_020839, NM_001346225, NM_001346226, NM_001346227, NM_001346228, NR_144399, NR_144400, NR_144401
Synonyms P80; SPG60; UAF1
Summary The protein encoded by this gene has been shown to interact with ubiquitin specific peptidase 1 (USP1), activating the deubiquitinating activity of USP1 and allowing it to remove the ubiquitin moiety from monoubiquitinated FANCD2. FANCD2 is ubiquitinated in response to DNA damage. [provided by RefSeq, Sep 2016]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.