Human DIP2 homolog B (DIP2B) activation kit by CRISPRa

CAT#: GA111630

DIP2B CRISPRa kit - CRISPR gene activation of human disco interacting protein 2 homolog B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DIP2B
• Locus ID: 57609
• Kit Components:

  GA111630G1, DIP2B gRNA vector 1 in pCas-Guide-CRISPRa

  GA111630G2, DIP2B gRNA vector 2 in pCas-Guide-CRISPRa

  GA111630G3, DIP2B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020849, NM_173602
• Summary: This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12. [provided by RefSeq, Aug 2011]