Human SLC7A14 activation kit by CRISPRa

CAT#: GA111703

SLC7A14 CRISPRa kit - CRISPR gene activation of human solute carrier family 7 member 14

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC7A14
• Locus ID: 57709
• Kit Components:

  GA111703G1, SLC7A14 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111703G2, SLC7A14 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111703G3, SLC7A14 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020949, N64525
• Synonyms: PPP1R142
• Summary: This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014]