Human PP4R4 (PPP4R4) activation kit by CRISPRa

CAT#: GA111710

PPP4R4 CRISPRa kit - CRISPR gene activation of human protein phosphatase 4 regulatory subunit 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP4R4
• Locus ID: 57718
• Kit Components:

  GA111710G1, PPP4R4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111710G2, PPP4R4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111710G3, PPP4R4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020958, NM_058237, NM_001348142, NM_001348143, NM_001348144, NM_001348145, NR_145441
• Synonyms: CFAP14; KIAA1622; PP4R4
• Summary: The protein encoded by this gene is a HEAT-like repeat-containing protein. The HEAT repeat is a tandemly repeated, 37-47 amino acid long module occurring in a number of cytoplasmic proteins. Arrays of HEAT repeats form a rod-like helical structure and appear to function as protein-protein interaction surfaces. The repeat-containing region of this protein has some similarity to the constant regulatory domain of the protein phosphatase 2A PR65/A subunit. The encoded protein binds protein serine/threonine phosphatase 4c in the cytoplasm. [provided by RefSeq, Jan 2017]