Human MPP4 activation kit by CRISPRa

CAT#: GA111806

MPP4 CRISPRa kit - CRISPR gene activation of human membrane palmitoylated protein 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MPP4
• Locus ID: 58538
• Kit Components:

  GA111806G1, MPP4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111806G2, MPP4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111806G3, MPP4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_033066
• Synonyms: ALS2CR5; DLG6
• Summary: This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family, with an N-terminal PDZ domain, a central src homology 3 region (SH3), and a C-terminal guanylate kinase-like (GUK) domain. The protein is localized to the outer limiting membrane in the retina, and is thought to function in photoreceptor polarity and the organization of specialized intercellular junctions. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]