Human IL22RA1 activation kit by CRISPRa

CAT#: GA111807

IL22RA1 CRISPRa kit - CRISPR gene activation of human interleukin 22 receptor subunit alpha 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL22RA1
• Locus ID: 58985
• Kit Components:

  GA111807G1, IL22RA1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111807G2, IL22RA1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111807G3, IL22RA1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021258
• Synonyms: CRF2-9; IL22R; IL22R1
• Summary: The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]