Human AASDHPPT activation kit by CRISPRa

CAT#: GA111863

AASDHPPT CRISPRa kit - CRISPR gene activation of human aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AASDHPPT
• Locus ID: 60496
• Kit Components:

  GA111863G1, AASDHPPT gRNA vector 1 in pCas-Guide-CRISPRa

  GA111863G2, AASDHPPT gRNA vector 2 in pCas-Guide-CRISPRa

  GA111863G3, AASDHPPT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015423
• Synonyms: AASD-PPT; CGI-80; LYS2; LYS5
• Summary: The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008]