Human AGBL5 activation kit by CRISPRa

CAT#: GA111865

AGBL5 CRISPRa kit - CRISPR gene activation of human ATP/GTP binding protein like 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AGBL5
• Locus ID: 60509
• Kit Components:

  GA111865G1, AGBL5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111865G2, AGBL5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111865G3, AGBL5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001035506, NM_001035507, NM_021831, NR_104246, NR_138023
• Summary: This gene encodes a metallocarboxypeptidase involved in protein deglutamylation and a member of the peptidase M14 family of proteins. The encoded protein has been described as a "dual-functional" deglutamylase that can remove glutamate residues from both carboxyl termini and side chains of protein substrates. This deglutamylase activity may be important in antiviral immunity. Mutations in this gene are associated with retinitis pigmentosa. [provided by RefSeq, Jul 2016]