Human RINT1 activation kit by CRISPRa

CAT#: GA111872

RINT1 CRISPRa kit - CRISPR gene activation of human RAD50 interactor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RINT1
• Locus ID: 60561
• Kit Components:

  GA111872G1, RINT1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111872G2, RINT1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111872G3, RINT1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021930, NM_001346599, NM_001346600, NM_001346601, NM_001346603, NR_144478
• Synonyms: RINT-1
• Summary: This gene encodes a protein first identified for its ability to interact with the RAD50 double strand break repair protein, with the resulting interaction implicated in the regulation of cell cycle progression and telomere length. The encoded protein may also play a role in trafficking of cellular cargo from the endosome to the trans-Golgi network. Mutations in this gene may be associated with breast cancer in human patients. [provided by RefSeq, Oct 2016]