Human RNF123 activation kit by CRISPRa

CAT#: GA111898

RNF123 CRISPRa kit - CRISPR gene activation of human ring finger protein 123

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RNF123
• Locus ID: 63891
• Kit Components:

  GA111898G1, RNF123 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111898G2, RNF123 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111898G3, RNF123 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_022064, NR_135218
• Synonyms: FP1477; KPC1
• Summary: The protein encoded by this gene contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]