Human CIDE C (CIDEC) activation kit by CRISPRa

CAT#: GA111918

CIDEC CRISPRa kit - CRISPR gene activation of human cell death inducing DFFA like effector c

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CIDEC
• Locus ID: 63924
• Kit Components:

  GA111918G1, CIDEC gRNA vector 1 in pCas-Guide-CRISPRa

  GA111918G2, CIDEC gRNA vector 2 in pCas-Guide-CRISPRa

  GA111918G3, CIDEC gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199551, NM_001199552, NM_001199623, NM_001321142, NM_001321143, NM_001321144, NM_022094
• Synonyms: CIDE-3; CIDE3; FPLD5; FSP27
• Summary: This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A pseudogene of this gene is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]