Human p53 AIP1 (TP53AIP1) activation kit by CRISPRa

CAT#: GA111938

TP53AIP1 CRISPRa kit - CRISPR gene activation of human tumor protein p53 regulated apoptosis inducing protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TP53AIP1
• Locus ID: 63970
• Kit Components:

  GA111938G1, TP53AIP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111938G2, TP53AIP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111938G3, TP53AIP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001195194, NM_001195195, NM_001251964, NM_022112
• Synonyms: P53AIP1
• Summary: This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]