Human STRA6 activation kit by CRISPRa

CAT#: GA112018

STRA6 CRISPRa kit - CRISPR gene activation of human stimulated by retinoic acid 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: STRA6
• Locus ID: 64220
• Kit Components:

  GA112018G1, STRA6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112018G2, STRA6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112018G3, STRA6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142617, NM_001142618, NM_001142619, NM_001142620, NM_001199040, NM_001199041, NM_001199042, NM_022369
• Synonyms: MCOPCB8; MCOPS9; PP14296
• Summary: The protein encoded by this gene is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9). Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]