Human CERK activation kit by CRISPRa

CAT#: GA112142

CERK CRISPRa kit - CRISPR gene activation of human ceramide kinase


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol CERK
Locus ID 64781
Kit Components

GA112142G1, CERK gRNA vector 1 in pCas-Guide-CRISPRa

GA112142G2, CERK gRNA vector 2 in pCas-Guide-CRISPRa

GA112142G3, CERK gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_022766, NM_182661
Synonyms dA59H18.2; dA59H18.3; hCERK; LK4
Summary CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]). [supplied by OMIM, Mar 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.